SUBSCRIBE

Breaking News on Supplements, Health & Nutrition - Europe US edition | APAC edition

Health condition news > Oral/Gum health

Probiotic shows post-treatment throat infection efficacy in children

Post a commentBy Will Chu , 12-Dec-2016
Last updated on 12-Dec-2016 at 14:02 GMT2016-12-12T14:02:11Z

Studies have extolled the virtues of maintaining a beneficial microbiome in the oral cavity through probiotic supplementation. ©iStock/CREATISTA
Studies have extolled the virtues of maintaining a beneficial microbiome in the oral cavity through probiotic supplementation. ©iStock/CREATISTA

Evidence for the BLIS K12 probiotic strain's role in oral health continues to build momentum as a study highlights its protective effects against multiple non-streptococcal infections even after its use was stopped.

A treatment period of 90 days followed by a nine month follow-up found a 90% reduction in the episodes of streptococcal pharyngitis in children compared to the untreated control group.

In addition, children in the BLIS K12 probiotic group showed a significantly lower number of episodes of tracheitis (95%), viral pharyngitis (90%), rhinitis (89%), flu (87%), laryngitis (98%), acute otitis media (100%) and enteritis (75%).

Stratum Nutrition and Blis Technologies’ BLIS K12 probiotic strain has been shown to reduce streptococcal pharyngitis and acute otitis media in children, as well as streptococcal pharyngitis in adults. However, this is the first study that demonstrates its long-term effectiveness post-treatment.

Streptococcal pharyngitis, which is also known as 'strep throat', is an infection of the back of the throat including the tonsils caused by group A streptococcus.

The infection is a common bacterial infection in children. Several European investigations which have examined the carriage rates in children and adults found the highest infection rate to be in subjects aged 14 years or less (10.9%).

Strep study

Some preliminary studies have indicated that BLIS K12 may also help prevent episodes of oropharyngeal infections of viral origin. ©iStock/VladimirFLoyd

Lead researcher Dr Francesco Di Pierro from the University of Parma in Italy enrolled 124 male and female children between the ages of 3 and 10 years.

48 children who displayed streptococcal pharyngitis the previous year were given BLIS K12 probiotic.

76 children who did not experience streptococcal pharyngitis in the previous year were enrolled into the untreated control group.

The BLIS K12 probiotic was administered for 90 days with an additional 9-month follow-up.

The team reported a 90% reduction of streptococcal pharyngitis cases in children taking the BLIS K12 probiotic (154 episodes vs. 16 episodes). In the untreated control group, actual episodes increased by appoximately 30%.

“These new findings demonstrate a persistent, protective effect even after cessation of usage,” said Dr Joseph Evans, founder & president of consulting and contract research firm P & N Development Ventures.

“Since standard of care treatments for these unpleasant conditions are limited and are associated with absences from school and work, safe and effective prophylactic supplements would be welcomed by parents and practitioners.”

Probiotic profile

Whilst the results of this study appear to show much promise, the authors acknowledge that the observational study method used meant the results could not be used to draw firm conclusions.

In addition they also recognised that the study might contain significant bias due to the relatively small number of treated subjects and the absence of a control, placebo, or alternative probiotic treatment.

Source: Drug, Healthcare and Patient Safety

Published online ahead of print, doi.org/10.2147/DHPS.S117214

“Positive clinical outcomes derived from using Streptococcus salivarius K12 to prevent streptococcal pharyngotonsillitis in children: a pilot investigation.”

Authors: Di Pierro F, Colombo M, Zanvit A, Rottoli AS

Post a comment

Comment title *
Your comment *
Your name *
Your email *

We will not publish your email on the site

I agree to Terms and Conditions

These comments have not been moderated. You are encouraged to participate with comments that are relevant to our news stories. You should not post comments that are abusive, threatening, defamatory, misleading or invasive of privacy. For the full terms and conditions for commenting see clause 7 of our Terms and Conditions ‘Participating in Online Communities’. These terms may be updated from time to time, so please read them before posting a comment. Any comment that violates these terms may be removed in its entirety as we do not edit comments. If you wish to complain about a comment please use the "REPORT ABUSE" button or contact the editors.

Related products

Live Supplier Webinars

Polyphenols tipped to become the way to innovate in Sports Nutrition
Fytexia
Alpha & Omega in Sports Nutrition – Using Omega 3’s and A-GPC to improve performance and recovery.
KD Pharma
Orally bioavailable standardized botanical derivatives in sport nutrition: special focus on recovery in post-intense physical activities
Indena
Collagen in motion: move freely and keep your injuries in check
Leading manufacturer of gelatine and collagen peptides
Life’s too short for slow proteins. Whey proteins hydrolysates: Fast delivery for enhanced performance
Arla Foods Ingredients
What it Takes to Compete and Win in Today’s Sports Nutrition Market
Capsugel
Sports Nutrition Snapshot: Key regional drivers and delivery format innovations
William Reed Business Media
Gutsy performance: How can microbiome modulation help athletes and weekend warriors
William Reed Business Media
Pushing the boundaries: Where’s the line between ‘cutting edge nutrition’ and doping
William Reed Business Media

On demand Supplier Webinars

High-amylose maize starch may reduce the risk of type 2 diabetes: what does this qualified health claim mean?
Ingredion
Balancing Innovation and Risk in Sports Nutrition Ingredients
NSF-International
Explaining bio-hacking: is there a marketing opportunity for food companies?
William Reed Business Media
Personalized Nutrition – how an industry can take part in shaping the future of Nutrition
BASF Nutrition & Health
Find out Nutritional and ingredient lifecycle solutions and strategies!
Roquette
Is the time rIpe for I-nutrition?
William Reed Business Media
The Advantage of Outsourcing Fermentation-based Manufacturing Processes
Evonik Health Care
All supplier webinars