SUBSCRIBE

Breaking News on Supplements, Health & Nutrition - Europe US edition | APAC edition

News > Research

Read more breaking news

 

 

Fish oil, glucosamine and chondroitin lead the way for anti-inflammatory potential: Study

1 commentBy Stephen DANIELLS , 11-Dec-2012

Fish oil, glucosamine and chondroitin lead the way for anti-inflammatory potential: Study

Regular use of dietary supplements containing fish oil, or glucosamine and chondroitin may reduce markers of inflammation by up to 22%, says a new study.

The magnitude of the reduction observed in levels of C-reactive protein (CRP), an established marker of inflammation, is similar to levels observed with statins, report researchers from Fred Hutchinson Cancer Research Center in Seattle and the University of Washington, Seattle.

“This study adds biologic plausibility to previous studies which have shown beneficial effects of these supplements on chronic diseases,” they wrote in the American Journal of Epidemiology .

“Given the number of diseases with which inflammation is associated, such as cancer and cardiovascular disease, there is a need to find safe and effective ways to reduce inflammation.

“Research suggests that these 3 supplements have excellent safety profiles, supporting their potential role in disease prevention. It is therefore important that the potential anti-inflammatory role of these supplements be further investigated.”

And the others?

On the flip side, the Seattle-based scientists report that no impact on CRP levels was found for a range of other supplements, including MSM, pycnogenol-containing supplements, garlic, ginkgo, or saw palmetto.

By way of explanation, they noted: “Power may have been limited to detect associations in less commonly used supplements; it is also possible that these supplements may affect inflammation downstream of CRP or that these supplements may not be associated with inflammation in humans.”

Study details

Elizabeth Kantor and her co-workers analyzed data from a nationally representative sample of 9,947 adults from the National Health and Nutrition Examination Survey.

The results showed that with regular use of glucosamine, chondroitin, and fish oil supplements was associated with reductions in CRP of 17%, 22%, and 16%, respectively.

“To our knowledge, this is the largest study that has investigated the association between use of glucosamine and chondroitin supplements and a marker of inflammation in humans,” they said.

“[Other] studies, plus our current study in a representative US population, provide evidence for the anti-inflammatory effects of long-chain omega-3 PUFAs in humans, and they support one of several mechanisms by which long-chain omega-3 PUFA intake may reduce the risk of cardiovascular disease, some cancers, and total mortality.”

Source: American Journal of Epidemiology
2012, Volume 176, Number 11, Pages 1002-13. doi: 10.1093/aje/kws186
“Association between use of specialty dietary supplements and C-reactive protein concentrations”
Authors: E.D. Kantor, J.W. Lampe, T.L. Vaughan, U. Peters, C.D. Rehm, E. White

1 comment (Comments are now closed)

the pycnogenol quoted wasn't Pycnogenol

The review article is indeed very interesting. However, the terminology "pycnogenol" was erroneously used for a grape seed (Chacon et al., 2009) and hexameric procyanidin of undefined source (Erlejman et al., 2008). These were the only studies on "pycnogenol" cited in the review. Moreover, these were in vitro tests only!

There is published research available on CRP-lowering effects of Pycnogenol in arthritis patients (Belcaro et al., Redox Report 13: 271-276, 2008)

Report abuse

Posted by Frank Schonlau
13 December 2012 | 11h062012-12-13T11:06:14Z

Related products

Live Supplier Webinars

Polyphenols tipped to become the way to innovate in Sports Nutrition
Fytexia
Orally bioavailable standardized botanical derivatives in sport nutrition: special focus on recovery in post-intense physical activities
Indena
Collagen in motion: move freely and keep your injuries in check
Leading manufacturer of gelatine and collagen peptides
Life’s too short for slow proteins. Whey proteins hydrolysates: Fast delivery for enhanced performance
Arla Foods Ingredients
What it Takes to Compete and Win in Today’s Sports Nutrition Market
Capsugel
Sports Nutrition Snapshot: Key regional drivers and delivery format innovations
William Reed Business Media
Gutsy performance: How can microbiome modulation help athletes and weekend warriors
William Reed Business Media
Pushing the boundaries: Where’s the line between ‘cutting edge nutrition’ and doping
William Reed Business Media
Alpha & Omega in Sports Nutrition – Using Omega 3’s and A-GPC to improve performance and recovery.
KD Pharma

On demand Supplier Webinars

High-amylose maize starch may reduce the risk of type 2 diabetes: what does this qualified health claim mean?
Ingredion
Balancing Innovation and Risk in Sports Nutrition Ingredients
NSF-International
Explaining bio-hacking: is there a marketing opportunity for food companies?
William Reed Business Media
Personalized Nutrition – how an industry can take part in shaping the future of Nutrition
BASF Nutrition & Health
Find out Nutritional and ingredient lifecycle solutions and strategies!
Roquette
Is the time rIpe for I-nutrition?
William Reed Business Media
The Advantage of Outsourcing Fermentation-based Manufacturing Processes
Evonik Health Care
All supplier webinars