SUBSCRIBE

Breaking News on Supplements, Health & Nutrition - Europe US edition | APAC edition

News > Research

Read more breaking news

 

 

New B vitamin discovered in Japan

25-Apr-2003

Japanese researchers have discovered a new vitamin that has an important role in immune response and fertility in mice. The chemical, pyrroloquinoline quinone (PQQ), may have a similar function in humans, they said.

The team from the Institute of Physical and Chemical Research in Tokyo report that they have found a new molecular function of PQQ, first discovered in 1979, leading them to propose its classification as a new B vitamin.

Researchers fed mice a PQQ-deficient diet and found that they grew slowly, had fragile skin and a reduced immune response, and also had problems reproducing. It is thought that because vitamins that have an important effect on mice usually act in the same way in humans, this vitamin may be vital for humans too.

Writing in this week's issue of Nature, Takaoki Kasahara and Tadafumi Kato identify PQQ's role in degrading the amino acid lysine in mice. They found that PQQ generates an enzyme that is required for the reaction to occur.

They explain that PQQ is acting as a redox cofactor in this reaction, just as nicotinamides and flavins act in other enzyme-catalysed redox reactions. They are classified as vitamins because they must be supplied in the diet.

PQQ is believed to be the first new vitamin to be discovered since 1948, and will join niacin/nicotinic acid (vitamin B3) and riboflavin (vitamin B2), in the B vitamin series. There are 13 other known vitamins, organic compounds required in trace amounts for normal growth and metabolic processes.

PQQ is not normally included in multi-vitamin tablets but can be found in vegetables such as parsley, green peppers and kiwi fruit and some meat.

More research is needed to explain the low fertility in mice and find out if the vitamin has a similar role in humans.

Live Supplier Webinars

Polyphenols tipped to become the way to innovate in Sports Nutrition
Fytexia
Orally bioavailable standardized botanical derivatives in sport nutrition: special focus on recovery in post-intense physical activities
Indena
Collagen in motion: move freely and keep your injuries in check
Leading manufacturer of gelatine and collagen peptides
Life’s too short for slow proteins. Whey proteins hydrolysates: Fast delivery for enhanced performance
Arla Foods Ingredients
What it Takes to Compete and Win in Today’s Sports Nutrition Market
Capsugel
Sports Nutrition Snapshot: Key regional drivers and delivery format innovations
William Reed Business Media
Gutsy performance: How can microbiome modulation help athletes and weekend warriors
William Reed Business Media
Pushing the boundaries: Where’s the line between ‘cutting edge nutrition’ and doping
William Reed Business Media
Alpha & Omega in Sports Nutrition – Using Omega 3’s and A-GPC to improve performance and recovery.
KD Pharma

On demand Supplier Webinars

High-amylose maize starch may reduce the risk of type 2 diabetes: what does this qualified health claim mean?
Ingredion
Balancing Innovation and Risk in Sports Nutrition Ingredients
NSF-International
Explaining bio-hacking: is there a marketing opportunity for food companies?
William Reed Business Media
Personalized Nutrition – how an industry can take part in shaping the future of Nutrition
BASF Nutrition & Health
Find out Nutritional and ingredient lifecycle solutions and strategies!
Roquette
Is the time rIpe for I-nutrition?
William Reed Business Media
The Advantage of Outsourcing Fermentation-based Manufacturing Processes
Evonik Health Care
All supplier webinars