SUBSCRIBE

Breaking News on Supplements, Health & Nutrition - Europe US edition | APAC edition

News > Research

Read more breaking news

 

 

No evidence of link between fruit and veg consumption and reduction in overall cancer cases: Major Japan study

By Gary Scattergood+

02-Feb-2017
Last updated on 02-Feb-2017 at 10:01 GMT2017-02-02T10:01:26Z

“The results do not provide evidence for inverse associations of fruit or vegetable consumption with risk of overall cancer incidence,” state researchers in Japan.
“The results do not provide evidence for inverse associations of fruit or vegetable consumption with risk of overall cancer incidence,” state researchers in Japan.

There is insufficient evidence of a link between fruit and vegetable consumption and a reduction in the number of overall cancer cases, according to a pooled analysis of large-scale cohort studies from Japan.

Despite comparatively clear associations between cardiovascular disease and fruit and vegetable intake, a series of recent reports from large-scale cohort studies involving more than 100,000 subjects reported none or only very small inverse associations between fruit and vegetable intake and overall cancer incidence.

“To date, however, no such data have been reported for Asian populations,” said researchers led by Shizuka Sasazuki from the National Cancer Center in Tokyo.

“[Therefore], to provide some indication of the net impact of fruit and vegetable consumption on overall cancer prevention, we examined these associations in a pooled analysis of large-scale cohort studies in Japanese populations.”

They analysed original data from four cohort studies that measured fruit and vegetable consumption using validated questionnaires at baseline. Hazard ratios in the individual studies were calculated, with adjustment for a common set of variables, and combined using a random-effects model.

The present study included 191,519 subjects (91,779 men and 99,740 women) and 17,681 cases of overall cancer (10,960 men and 6721 women).

“Among both men and women, no significant inverse associations were found between fruit or vegetable intake and the risk of overall cancer, whether combined or separated,” they wrote. 

Furthermore, no specific fruit or vegetable showed significant inverse association with the risk of overall cancer.

In a sub-analysis based on intake frequency, which included an additional two cohort studies, with a total of 254,314 subjects (120,964 men and 133,350 women) and 22,442 cases of overall cancer (13,729 men and 8713 women), no association was again found between fruit or vegetable consumption and overall cancer risk among either gender.

Impact undetectable

This pooled analysis of major population-based cohort studies in Japan, which included data on 17,681 cancer cases, revealed no significant inverse associations of fruit or vegetable consumption with the risk of overall cancer, whether combined or separated by specific groups,” they added.

“Further, these results did not substantially change in stratified analyses by smoking status or alcohol drinking. Moreover, no significant inverse associations were shown when outcomes were confined to smoking-related cancers.

“To our knowledge, this pooled analysis included the largest number of overall cancer cases in an Asian population to date.”

Although the impact for overall cancer prevention was undetectable, the results do not contradict the possibly small but protective effect of fruit and vegetable intake for site-specific cancers, such as stomach cancer, lung cancer, or breast cancer by hormone receptor status, said the researchers.

“Therefore, in accordance with the biological plausibility, the recommendation that ‘higher consumption of several plant foods probably protects against cancers of various sites’ may still be applicable in Japan.”

Nevertheless, they concluded: “The results of this pooled analysis of large-scale population-based prospective cohort studies in Japan do not provide evidence for inverse associations of fruit or vegetable consumption with risk of overall cancer incidence.”

 

Source: Journal of Epidemiology

http://dx.doi.org/10.1016/j.je.2016.05.004

“Fruit and vegetable intake and the risk of overall cancer in Japanese: A pooled analysis of population-based cohort studies.”

Authors: Shizuka Sasazuki , et al.

Related products

Live Supplier Webinars

Polyphenols tipped to become the way to innovate in Sports Nutrition
Fytexia
Alpha & Omega in Sports Nutrition – Using Omega 3’s and A-GPC to improve performance and recovery.
KD Pharma
Orally bioavailable standardized botanical derivatives in sport nutrition: special focus on recovery in post-intense physical activities
Indena
Collagen in motion: move freely and keep your injuries in check
Leading manufacturer of gelatine and collagen peptides
Life’s too short for slow proteins. Whey proteins hydrolysates: Fast delivery for enhanced performance
Arla Foods Ingredients
What it Takes to Compete and Win in Today’s Sports Nutrition Market
Capsugel
Sports Nutrition Snapshot: Key regional drivers and delivery format innovations
William Reed Business Media
Gutsy performance: How can microbiome modulation help athletes and weekend warriors
William Reed Business Media
Pushing the boundaries: Where’s the line between ‘cutting edge nutrition’ and doping
William Reed Business Media

On demand Supplier Webinars

High-amylose maize starch may reduce the risk of type 2 diabetes: what does this qualified health claim mean?
Ingredion
Balancing Innovation and Risk in Sports Nutrition Ingredients
NSF-International
Explaining bio-hacking: is there a marketing opportunity for food companies?
William Reed Business Media
Personalized Nutrition – how an industry can take part in shaping the future of Nutrition
BASF Nutrition & Health
Find out Nutritional and ingredient lifecycle solutions and strategies!
Roquette
Is the time rIpe for I-nutrition?
William Reed Business Media
The Advantage of Outsourcing Fermentation-based Manufacturing Processes
Evonik Health Care
All supplier webinars

Promotional Features