SUBSCRIBE

Breaking News on Supplements, Health & Nutrition - Europe US edition | APAC edition

News > Research

Read more breaking news

 

 

Omega-3s again linked to lower heart failure risk

By Stephen Daniells , 24-Sep-2012
Last updated on 24-Sep-2012 at 16:25 GMT2012-09-24T16:25:05Z

Omega-3s again linked to lower heart failure risk

Consuming fish at least once a month, and increased blood levels of  ALA and DPA, may reduce the risk of heart failure, says a new study that adds to the heart health benefits of omega-3.

Data from over 20,000 people indicated that higher blood levels of ALA (alpha-linolenic acid) had a 34% lower risk, compared with people with lower levels, according to findings published in the American Journal of Clinical Nutrition.

In addition, the higher average levels of DPA (docosapentaenoic acid) were associated with a 45% reduction, compared with lower levels, report researchers from Brigham and Women’s Hospital and Harvard Medical School, and the University of Minnesota.

However, blood levels of EPA and DHA were not associated with heart failure risk, they added.

Benefits

The heart health benefits of fish oil, and the omega-3 fatty acids it contains, are well-documented, being first reported in the early 1970s by Dr Jorn Dyerberg  and his co-workers in The Lancet and The American Journal of Clinical Nutrition.

To date, the polyunsaturated fatty acids (PUFAs) have been linked to improvements in blood lipid levels, a reduced tendency of thrombosis, blood pressure and heart rate improvements, and improved vascular function.

Support

Commenting on the study’s findings, Harry Rice, PhD, VP of regulatory and scientific affairs for GOED, told NutraIngredients-USA that the results corroborate previous findings from the Cardiovascular Health Study demonstrating a lower risk of heart failure associated with modest fish intake.

“With respect to heart failure and Omega-3s, think GISSI-HF, a randomized clinical trial in which long-term administration of 1g/day of long-chain omega-3s (compared to placebo) to nearly 7000 patients with heart failure was effective in significantly reducing all-cause mortality.

“The results were particularly impressive when you consider that patients were being maintained on cocktails of cardio drugs.”

Study details

The Boston- and Minnesota-based researchers analyzed data from 1,572 people from a case-control study, and 19,097 people from a cohort. The mean age of the people at the time of the blood collection was 58.7.

Results showed that at least one serving of fish per month was associated with a 30% reduction in heart failure risk. There was a trend toward a lower risk for increased intakes of marine fatty acids, but this did not reach statistical significance.

“Because the study participants were male physicians, it is unclear whether the results are generalizable to women and the general population,” wrote the researchers.

“Our data are consistent with an inverse and nonlinear relation of plasma phospholipid ALA and DPA, but not EPA and DHA, with heart failure risk. Fish consumption greater than once per month was associated with a lower risk of heart failure.”

Source: American Journal of Clinical Nutrition
Published online ahead of print, doi: 10.3945/ajcn.112.042671
“Plasma and dietary omega-3 fatty acids, fish intake, and heart failure risk in the Physicians’ Health Study”
Authors: J.B. Wilk, M.Y. Tsai, N.Q. Hanson, J.M. Gaziano, L. Djousse

Related products

Live Supplier Webinars

Polyphenols tipped to become the way to innovate in Sports Nutrition
Fytexia
Alpha & Omega in Sports Nutrition – Using Omega 3’s and A-GPC to improve performance and recovery.
KD Pharma
Orally bioavailable standardized botanical derivatives in sport nutrition: special focus on recovery in post-intense physical activities
Indena
Collagen in motion: move freely and keep your injuries in check
Leading manufacturer of gelatine and collagen peptides
Life’s too short for slow proteins. Whey proteins hydrolysates: Fast delivery for enhanced performance
Arla Foods Ingredients
What it Takes to Compete and Win in Today’s Sports Nutrition Market
Capsugel
Sports Nutrition Snapshot: Key regional drivers and delivery format innovations
William Reed Business Media
Gutsy performance: How can microbiome modulation help athletes and weekend warriors
William Reed Business Media
Pushing the boundaries: Where’s the line between ‘cutting edge nutrition’ and doping
William Reed Business Media

On demand Supplier Webinars

High-amylose maize starch may reduce the risk of type 2 diabetes: what does this qualified health claim mean?
Ingredion
Balancing Innovation and Risk in Sports Nutrition Ingredients
NSF-International
Explaining bio-hacking: is there a marketing opportunity for food companies?
William Reed Business Media
Personalized Nutrition – how an industry can take part in shaping the future of Nutrition
BASF Nutrition & Health
Find out Nutritional and ingredient lifecycle solutions and strategies!
Roquette
Is the time rIpe for I-nutrition?
William Reed Business Media
The Advantage of Outsourcing Fermentation-based Manufacturing Processes
Evonik Health Care
All supplier webinars