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NeuroFactor Whole Coffee Fruit Concentrate is a patented product from the whole fruit of the coffee plant, Coffea arabica. In a double-blind, placebo-controlled pilot human clinical study, NeuroFactor increased levels of Brain-Derived Neurotrophic Factor (BDNF) by 143% on average. BDNF is a protein active in the brain and central and peripheral nervous systems with a critical role in neuron development and repair and in protecting against neuro-degeneration. BDNF is important for learning, memory, alertness, mood, controlling body weight, and controlling energy metabolism.
The results indicate NeuroFactor could be used for modulation of BDNF-dependent health conditions in humans. No significant increase in BDNF was seen in subjects taking green coffee bean extract, natural coffee caffeine, grape seed extract, or chlorogenic acid.