Supplementation with the proprietary ingredient blend led to 6.4 per cent greater weight loss, and a 6.97 greater loss of body fat than placebo, according to results from the randomised, double blind, parallel-controlled study. Lakshmi Prakash, PhD, VP innovation and business development at Sabinsa told NutraIngredients that the study has not yet been published in a peer reviewed journal, but an article is being prepared for publication in the near future. NutraIngredients.com has not seen the full data. The study sees the company build the science behind its blended ingredient - a necessary endeavour if the company wants to stand out in an increasingly competitive weight loss market. Approximately one third of Americans are obese and Euromonitor International estimates the US weight management supplements market to be worth $3.93bn, while the European market is valued at $0.93bn in 2005. LeanGard is a blend of ForsLean, Garcitrin and Bioperine. The first is an extract derived from Coleus forskohlii roots and reportedly helps to build lean body mass and optimize body composition through cAMP (cyclic adenosine monophosphate) activation. Garcitrin contains calcium salt hydroxycitric acid (HCA) and garcinol, a polyisoprenylated benzophenone isolated from Garcinia cambogia and Garcinia indica. These fruits are thought to reduce fatty acid, lipid synthesis as well as to improve lean body mass. Standardized piperine Bioperine is extracted from black pepper and is claimed to increase the absorption of nutrients in nutritional supplement formulations. New data The researchers, led by Noor Khan, MD, from Shifaa Hospital in Bangalore, India, recruited 50 overweight and obese subjects, (26 women) aged between 25 and 55, and randomly assigned them to receive either a daily dose of the proprietary blend (500 mg) or placebo for 12 weeks. At the end of the study period, 90 per cent of participants in the LeanGard group achieved more than five per cent reduction in body weight, while no one in the placebo group achieved this weight loss. This translated to a 7.45 per cent reduction in BMI, compared to a 1.09 per cent change in the placebo group. An increase in the basal metabolic rate (BMR) of 4.5 per cent was also observed in the LeanGard group, while people in the placebo group experienced at a 0.64 per cent mean increase. The ingredient was first presented at the Slimming Ingredients, Germany conference in March 2007.