Breaking News on Supplements, Health & Nutrition - Europe US edition | APAC edition

News > Research

Read more breaking news



Aged garlic shows blood pressure improvement benefits: Study

By Stephen Daniells , 17-Nov-2010

Daily supplements of an aged garlic extract may reduce systolic blood pressure by 10.2 mmHg, suggests new data from Australia.

Writing in Maturitas, scientists from the University of Adelaide report that the benefits were only observed in people with initial systolic pressure (SBP) of 140 mmHg or over, and that no effects were observed in people with lower SBP.

The study is reported to be the first to examine the effects of aged garlic extracts for reducing hypertension, and adds to the body of science supporting the potential cardiovascular benefits of garlic. Consumer awareness of the health benefits of garlic, mostly in terms of cardiovascular and immune system health, has benefited the supplements industry, particularly since consumers seek the benefits of garlic without the odours that accompany the fresh bulb.

The new study used supplementation with four capsules of aged garlic extract providing 960 mg containing 2.4 mg S-allylcysteine) daily for 12 weeks.

“Aged garlic extract is regarded as safe and more tolerable than garlic powder, and superior to raw or cooked garlic in relation to its antihypertensive properties,” explained the researchers. “In addition, the active component S-allylcysteine (SAC) in AGE is less volatile than allicin in garlic powder, and therefore more easily standardised.”

High blood pressure (hypertension),defined as having a systolic and diastolic blood pressure (BP) greater than 140 and 90 mmHg, is a major risk factor for cardiovascular disease (CVD) - a disease that causes almost 50 per cent of deaths in Europe, and reported to cost the EU economy an estimated €169bn ($202bn) per year.

Study details

The Adelaide-based scientists, led by Karin Ried from the School of Population Health and Clinical Practice, recruited 50 people with treated but uncontrolled hypertension to participate in their double-blind parallel randomised placebo-controlled trial.

The participants were randomly assigned to receive either a daily dose of aged garlic extract of 3.84 grams (Kyolic, Garlic High Potency Everyday Formula 112, Wakunga/Wagner) or placebo for 12 weeks. The garlic dose was said to be “equivalent to about 2.5 g of fresh garlic and comparable to the dosage used in the majority of previous trials on garlic supplements and blood pressure”.

Results showed a “marked difference” between the garlic and control groups in subjects with ‘uncontrolled hypertension’. On the other hand, no effects on diastolic blood pressure were observed between the groups, said the researchers.

“Future larger trials are needed to confirm our findings of effectiveness on systolic hypertension, ascertain the effect on diastolic hypertension, investigate dose–response relationships, examine effect in association to conventional blood pressure medication classes, and explore whether supplementation with molybdenum and vitamin B12 improves some patients’ tolerance of garlic,” they concluded.

Source: Maturitas
Volume 67, Issue 2, Pages 144-150
“Aged garlic extract lowers blood pressure in patients with treated but uncontrolled hypertension: A randomised controlled trial”
Authors: K. Ried, O.R. Frank, N.P. Stocks

Related products

Live Supplier Webinars

Polyphenols tipped to become the way to innovate in Sports Nutrition
Orally bioavailable standardized botanical derivatives in sport nutrition: special focus on recovery in post-intense physical activities
Collagen in motion: move freely and keep your injuries in check
Leading manufacturer of gelatine and collagen peptides
Life’s too short for slow proteins. Whey proteins hydrolysates: Fast delivery for enhanced performance
Arla Foods Ingredients
What it Takes to Compete and Win in Today’s Sports Nutrition Market
Sports Nutrition Snapshot: Key regional drivers and delivery format innovations
William Reed Business Media
Gutsy performance: How can microbiome modulation help athletes and weekend warriors
William Reed Business Media
Pushing the boundaries: Where’s the line between ‘cutting edge nutrition’ and doping
William Reed Business Media
Alpha & Omega in Sports Nutrition – Using Omega 3’s and A-GPC to improve performance and recovery.
KD Pharma

On demand Supplier Webinars

High-amylose maize starch may reduce the risk of type 2 diabetes: what does this qualified health claim mean?
Balancing Innovation and Risk in Sports Nutrition Ingredients
Explaining bio-hacking: is there a marketing opportunity for food companies?
William Reed Business Media
Personalized Nutrition – how an industry can take part in shaping the future of Nutrition
BASF Nutrition & Health
Find out Nutritional and ingredient lifecycle solutions and strategies!
Is the time rIpe for I-nutrition?
William Reed Business Media
The Advantage of Outsourcing Fermentation-based Manufacturing Processes
Evonik Health Care
All supplier webinars