SUBSCRIBE

Breaking News on Supplements, Health & Nutrition - Europe US edition | APAC edition

News > Research

Read more breaking news

 

 

Coffee consumption may reduce risk of liver cancer: Meta-analysis

1 comment

By Nathan Gray+

24-Oct-2013
Last updated on 24-Oct-2013 at 12:45 GMT2013-10-24T12:45:32Z

Coffee consumption may reduce risk of liver cancer: Meta-analysis

Consumption of coffee may reduce the risk of hepatocellular carcinoma (HCC), the most common type of liver cancer, by about 40%, according to a new meta-analysis.

Published in Clinical Gastroenterology and Hepatology, the research team performed a meta-analysis of articles published from 1996 through September 2012, ultimately studying 16 high-quality studies and a total of 3,153 cases.

The results of the analysis suggest that the risk of HCC is reduced by 40% for any coffee consumption vs no consumption, while some data indicated that consumption of three cups of coffee per day may reduce liver cancer risk by more than 50%.

"Our research confirms past claims that coffee is good for your health, and particularly the liver," said Dr Carlo La Vecchia from the Università degli Studi di Milan, Italy - lead author of the study.

"The favourable effect of coffee on liver cancer might be mediated by coffee's proven prevention of diabetes, a known risk factor for the disease, or for its beneficial effects on cirrhosis and liver enzymes," he suggested.

The Italian researchers said that despite the consistency of results across studies, time periods and populations, it is difficult to establish whether the association between coffee drinking and HCC is causal, or if this relationship may be partially attributable to the fact that patients with liver and digestive diseases often voluntarily reduce their coffee intake.

"It remains unclear whether coffee drinking has an additional role in liver cancer prevention," added Dr La Vecchia. "But, in any case, such a role would be limited as compared to what is achievable through the current measures."

Study details

La Vecchia and his colleagues said that their findings fill an important gap as the last meta-analysis was published in 2007, and since then there has been data published on more than 900 cases of HCC.

The team identified 16 high-quality studies published from 1996 through September 2012 - with pooled data for a total of 3,153 cases of HCC.

"The pooled estimate from the 6 studies published after 2007 was comparable with that of previous ones," said the researchers. "Thus, recent studies add up to the evidence that coffee drinkers have a 40% reduced risk of HCC compared with non-drinkers, and high drinkers have a more than 50% risk reduction."

The inverse relationship between coffee and HCC risk was consistent regardless of the subjects’ sex, alcohol drinking, or history of hepatitis or liver disease, they confirmed.

Source: Clinical Gastroenterology and Hepatology
Volume 11, Issue 11 , Pages 1413–1421.e1, doi: 10.1016/j.cgh.2013.04.039
"Coffee Reduces Risk for Hepatocellular Carcinoma: An Updated Meta-analysis"
Authors: Francesca Bravi, Cristina Bosetti, Alessandra Tavani, Silvano Gallus, Carlo La Vecchia

1 comment (Comments are now closed)

2 cups of coffe

i have learned from my previous study of coffee tht 2 cups of it is enough. more than 2 cups may cause other problems as it has high caffeine.

Report abuse

Posted by zoya
26 October 2013 | 11h132013-10-26T11:13:24Z

Related products

Live Supplier Webinars

Polyphenols tipped to become the way to innovate in Sports Nutrition
Fytexia
Orally bioavailable standardized botanical derivatives in sport nutrition: special focus on recovery in post-intense physical activities
Indena
Collagen in motion: move freely and keep your injuries in check
Leading manufacturer of gelatine and collagen peptides
Life’s too short for slow proteins. Whey proteins hydrolysates: Fast delivery for enhanced performance
Arla Foods Ingredients
What it Takes to Compete and Win in Today’s Sports Nutrition Market
Capsugel
Sports Nutrition Snapshot: Key regional drivers and delivery format innovations
William Reed Business Media
Gutsy performance: How can microbiome modulation help athletes and weekend warriors
William Reed Business Media
Pushing the boundaries: Where’s the line between ‘cutting edge nutrition’ and doping
William Reed Business Media
Alpha & Omega in Sports Nutrition – Using Omega 3’s and A-GPC to improve performance and recovery.
KD Pharma

On demand Supplier Webinars

High-amylose maize starch may reduce the risk of type 2 diabetes: what does this qualified health claim mean?
Ingredion
Balancing Innovation and Risk in Sports Nutrition Ingredients
NSF-International
Explaining bio-hacking: is there a marketing opportunity for food companies?
William Reed Business Media
Personalized Nutrition – how an industry can take part in shaping the future of Nutrition
BASF Nutrition & Health
Find out Nutritional and ingredient lifecycle solutions and strategies!
Roquette
Is the time rIpe for I-nutrition?
William Reed Business Media
The Advantage of Outsourcing Fermentation-based Manufacturing Processes
Evonik Health Care
All supplier webinars