A new 12-week clinical study has strengthened evidence that melon-derived superoxide dismutase (Sod) supplements can help reduce stress and fatigue and improve cognitive performance.
Volunteers taking proprietary Sod-B Extramel supplements in the trial reported a reduction of stress and physical fatigue, as well as an improvement of cognitive performances and overall life quality.
Results of the randomised, double-blind, placebo-controlled clinical study of 61 people have just been published in the journal Nutrients.
Volunteers were divided into two groups, with 29 given a placebo and 32 an oral supplement of Sod-B Extramel (140 IU Sod/day).
The volunteers were tested three times: Before supplementation, 28 days after the supplementation and 84 days after the supplementation.
The group taking Sod-B Extramel reported an 8.8% reduction of stress, 9.4% reduction in physical fatigue, as well as, 13.9% improvement of cognitive performances and 6.4% in overall life quality. Well-being parameters were evaluated by five validated psychometric evaluation scales, including questionnaires.
The report concluded that Sod-B supplementation appeared to be an effective way to reduce stress and fatigue, possibly due to enhancement of endogenous antioxidant defence and the subsequent reduction of oxidative stress in participants.
Sod-B Extramel is a proprietary coated freeze-dried melon juice concentrate from French supplier Bionov, that is highly concentrated in superoxide dismutase. It is sourced from a specific variety of Cantaloupe melon (Cucumis melo. L)
Sébastien Le Quéré, products manager at Bionov told Nutraingredients: “Sod-B Extramel is already on the market, and numerous nutritional products have already been formulated with this ingredient. This second major clinical study represents an efficient communication and business booster, by confirming the efficiency of Sod-B Extramel in the improvement of daily performances.”
The influence of Sod-B Extramel from Bionov was previously assessed in a pilot study, over 28 days which showed beneficial effects (Nutr. J. 2009, 8, 40). This second trial looked at the effects over a longer period of 84 days (12 weeks).
The Bionov Sod-B Extramel product is available with different coatings and is adapted for nutritional applications, dried formulations such as capsules, tablets, pills, as well as for instant drink applications such as sticks, sachets and syrups.
The trial was also supported by French cosmetics company Seppic.
2014, 6(6), 2348-2359; doi:10.3390/nu6062348
‘Dietary Supplementation with a Superoxide Dismutase-Melon Concentrate Reduces Stress, Physical and Mental Fatigue in Healthy People: A Randomised, Double-Blind, Placebo-Controlled Trial’
Authors: Julie Carillon, Claire Notin, Karine Schmitt, Guy Simoneau and Dominique Lacan