Breaking News on Supplements, Health & Nutrition - Europe US edition | APAC edition

News > Research

Read more breaking news



Oily fish may boost prostate cancer survival rate: Study

By Stephen Daniells , 24-Nov-2008

An increased intake of fish and omega-3-rich seafood may improve prostate cancer survival by 38 per cent, according to a new study.

The prospective cohort study with 20,167 men also found that men who ate five portions of fish per week had a 48 per cent improved survival rate from the disease than men who consumed only one portion per week.

Findings of the study, led by Jorge Chavarro from Harvard School of Public Health, are published in the current issue of the American Journal of Clinical Nutrition.

The study adds to a small but growing body of evidence linking fish consumption and omega-3 to potential cancer benefits. However, the same researchers reported results in the journal Cancer Epidemiology, Biomarkers & Prevention (doi: 10.1158/1055-9965.EPI-06-1033) last year that appear at odds with the new findings.

The earlier study found reported that higher intake of the omega-3 fatty acids DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid) may cut the risk of developing prostate cancer by 40 per cent. On the other hand, the new study reports no relationship between fish intake and the risk of prostate cancer.

Over half a million news cases of prostate cancer are diagnosed every year world wide, and the cancer is the direct cause of over 200,000 deaths. More worryingly, the incidence of the disease is increasing with a rise of 1.7 per cent over 15 years.

Study details

Chavarro and his co-workers used data from the Physician's Health Study. Over 20,000 men were followed for 382,144 person-years of follow-up, during which time 2,161 cases of prostate cancer were diagnosed and 230 deaths from the disease recorded. All of the men were free of the disease at the start of the study in 1983.

Both high fish and seafood omega-3 fatty acid intakes were associated with significant reductions in the risk of prostate cancer death men, compared to men with lower consumptions.

“These results suggest that fish intake is unrelated to prostate cancer incidence but may improve prostate cancer survival,” concluded the researchers.

Earlier study

The results appear at odds with the earlier study, which compared blood levels of polyunsaturated fatty acids in 476 men diagnosed with prostate cancer, and the same number of healthy controls.

Comparing men with the highest and lowest long-chain n-3 fatty acids (EPA, DPA, DHA), Chavarro and co-workers report that the highest intake was associated with a 41 per cent reduction in prostate cancer risk.

There have also been studies indicating relationships between the omega-3 to omega-6 ratio and prostate cancer. In August 2006, researchers from the David Geffen School of Medicine at UCLA reported that changing the ration of omega-3 to omega-6 in the typical Western diet might reduce prostate cancer tumour growth rates and PSA levels (Clinical Cancer Research, Vol. 12, Issue 15).

Source: American Journal of Clinical NutritionNovember 2008, Volume 88, Number 5, Pages 1297-1303"A 22-y prospective study of fish intake in relation to prostate cancer incidence and mortality"Authors: J.E. Chavarro, M.J. Stampfer, M.N. Hall, H.D. Sesso, J. Ma

Related products

Live Supplier Webinars

Polyphenols tipped to become the way to innovate in Sports Nutrition
Alpha & Omega in Sports Nutrition – Using Omega 3’s and A-GPC to improve performance and recovery.
KD Pharma
Orally bioavailable standardized botanical derivatives in sport nutrition: special focus on recovery in post-intense physical activities
Collagen in motion: move freely and keep your injuries in check
Leading manufacturer of gelatine and collagen peptides
Life’s too short for slow proteins. Whey proteins hydrolysates: Fast delivery for enhanced performance
Arla Foods Ingredients
What it Takes to Compete and Win in Today’s Sports Nutrition Market
Sports Nutrition Snapshot: Key regional drivers and delivery format innovations
William Reed Business Media
Gutsy performance: How can microbiome modulation help athletes and weekend warriors
William Reed Business Media
Pushing the boundaries: Where’s the line between ‘cutting edge nutrition’ and doping
William Reed Business Media

On demand Supplier Webinars

High-amylose maize starch may reduce the risk of type 2 diabetes: what does this qualified health claim mean?
Balancing Innovation and Risk in Sports Nutrition Ingredients
Explaining bio-hacking: is there a marketing opportunity for food companies?
William Reed Business Media
Personalized Nutrition – how an industry can take part in shaping the future of Nutrition
BASF Nutrition & Health
Find out Nutritional and ingredient lifecycle solutions and strategies!
Is the time rIpe for I-nutrition?
William Reed Business Media
The Advantage of Outsourcing Fermentation-based Manufacturing Processes
Evonik Health Care
All supplier webinars