Breaking News on Supplements, Health & Nutrition - Europe US edition | APAC edition

News > Research

Read more breaking news



Yeast beta-glucan shows benefits for ragweed allergy sufferers

By Stephen DANIELLS , 04-Jan-2013
Last updated on 07-Feb-2013 at 22:37 GMT2013-02-07T22:37:06Z

Yeast beta-glucan shows benefits for ragweed allergy sufferers

Supplements of the beta-glucan based ingredient Wellmune WGP may reduce symptoms and severity of ragweed allergy, and boost overall ‘quality of life’, says a new study.

Four weeks of supplementation with Biothera’s branded ingredient were associated with a 28% and 52% reduction in total allergy symptoms and symptom severity, respectively, according to findings published in Food Science & Nutrition .

The supplement was also associated with improved sleep, reduced nasal and eye symptoms, better mood, and increased vigor, report researchers from Utah-based GLH Nutrition, LLC.

“The potential usefulness of beta-glucan as a food additive is supported by work showing that yeast beta-glucan exhibits immune-modulating function; however, our study is one of few that have investigated whether beta-glucan can alleviate the symptoms of allergic disease,” wrote the researchers, led by Shawn Talbott, PhD.

The ingredient

Wellmune WGP, derived from the cell walls of a proprietary strain of yeast (Saccharomyces cerevisiae) via a patented manufacturing process, is a natural carbohydrate that activates key immune cells.

Designed for use with foods, beverages and premium supplements, Wellmune can be used in a large number of subcategories in each segment. For example, beverages example, may include dairy, waters, teas, juices, sports drinks and other functional beverages, as well as powdered beverages.

“Beta-glucans can be given orally, are typically less costly than immunotherapies, and have fewer side effects than immunotherapies,” explained Dr Talbott and his co-workers. “Furthermore, they occur naturally, and are effective.”

The new study, funded by Biothera, tested the effects of the ingredient in people with self-described ‘moderate’ ragweed allergy. Forty-eight participants with an average age of 36 were randomly assigned to receive either 250 milligrams per day of Wellmune WGP or 250 mg per day of rice flour (placebo) for four weeks.

While the supplements had no effect on IgE levels, allergy symptoms and severity decreased significantly, as measured by the Visual Analog Scale, for the Wellmune group, compared with placebo.

In addition, measures of quality of life improved by 56% in the beta-glucan group, compared with placebo, while

Study participants given WGP reported increased physical health (11%), energy (19%), and emotional well-being (7%) compared with study participants given the placebo (RAND SF-36 Medical Outcomes Study). The WGP group also reported decreased sleep problems (53%), reduced nasal symptoms (59%), eye symptoms (57%), non-nasal symptoms (50%), activities (53%), emotions (57%), and improved quality of life (QOL) (56%), as well as improved global mood state (13%).


“The findings suggest that Wellmune WGP can play an effective role in reducing seasonal allergy symptoms among ragweed allergy sufferers,” said Dr Talbott. “While these results are encouraging, additional studies including more study participants should be conducted.”

The results were welcomed by Biothera CEO Richard Mueller. “A daily regimen including all-natural Wellmune WGP is well-documented to safely support immune health, a key contributor to overall health and well-being,” he said.

“Given the important role immune modulation plays in managing symptoms, allergy sufferers who choose foods, beverages and supplements with clinically proven immune support can help ease their discomfort during allergy season.”

Source: Food Science & Nutrition
Published online ahead of print, doi: 10.1002/fsn3.11
“β-Glucan supplementation, allergy symptoms, and quality of life in self-described ragweed allergy sufferers”
Authors: S.M. Talbott, J.A. Talbott, T.L. Talbott, E. Dingler

Related products

Live Supplier Webinars

Polyphenols tipped to become the way to innovate in Sports Nutrition
Alpha & Omega in Sports Nutrition – Using Omega 3’s and A-GPC to improve performance and recovery.
KD Pharma
Orally bioavailable standardized botanical derivatives in sport nutrition: special focus on recovery in post-intense physical activities
Collagen in motion: move freely and keep your injuries in check
Leading manufacturer of gelatine and collagen peptides
Life’s too short for slow proteins. Whey proteins hydrolysates: Fast delivery for enhanced performance
Arla Foods Ingredients
What it Takes to Compete and Win in Today’s Sports Nutrition Market
Sports Nutrition Snapshot: Key regional drivers and delivery format innovations
William Reed Business Media
Gutsy performance: How can microbiome modulation help athletes and weekend warriors
William Reed Business Media
Pushing the boundaries: Where’s the line between ‘cutting edge nutrition’ and doping
William Reed Business Media

On demand Supplier Webinars

High-amylose maize starch may reduce the risk of type 2 diabetes: what does this qualified health claim mean?
Balancing Innovation and Risk in Sports Nutrition Ingredients
Explaining bio-hacking: is there a marketing opportunity for food companies?
William Reed Business Media
Personalized Nutrition – how an industry can take part in shaping the future of Nutrition
BASF Nutrition & Health
Find out Nutritional and ingredient lifecycle solutions and strategies!
Is the time rIpe for I-nutrition?
William Reed Business Media
The Advantage of Outsourcing Fermentation-based Manufacturing Processes
Evonik Health Care
All supplier webinars