SUBSCRIBE

Breaking News on Supplements, Health & Nutrition - Europe US edition | APAC edition

News > Research

Read more breaking news

 

 

Curcumin may match exercise for heart health benefits: RCT data

By Stephen Daniells , 31-Oct-2012
Last updated on 31-Oct-2012 at 14:53 GMT2012-10-31T14:53:53Z

Curcumin may match exercise for heart health benefits: RCT data

Daily supplements of curcumin may benefit cardiovascular health to the same extent as exercise for postmenopausal women, says new data from a clinical trial from Japan.

Vascular health, as measured by flow-mediated dilation (FMD), improved equally in groups of women receiving the curcumin supplements and those receiving aerobic exercise training, according to findings published in Nutrition Research .

A recent study in the British Journal of Nutrition  indicated that decreased FMD is reported to be a predictor of future adverse cardiovascular events, with every 1% decrease in FMD associated with a 12% increase in risk.

 “Therefore, regular ingestion of curcumin could be a preventive measure against cardiovascular disease in postmenopausal women,” they wrote.

“Furthermore, our results suggest that curcumin may be a potential alternative […] for patients who are unable to exercise.”

Benefits

Curcumin, the natural pigment that gives the spice turmeric its yellow color, has increasingly come under the scientific spotlight in recent years, with studies investigating its potential health benefits.

As a result, curcumin has been linked to a range of health benefits, including potential protection against prostate cancer, Alzheimer’s, protection against heart failure, diabetes, and arthritis.

The new study suggests that endothelial function may also be added to the list of potential benefits from curcumin.

Endothelial health is gaining more visibility with the product formulation community. One of the sessions at the recent IFT show in Las Vegas in June focused on the category as a possible avenue for new health claims.

A recent article by NutraIngredients-USA discussed the potential of the market and how to communicate the benefits to consumers.

Study details

Researchers from the University of Tsukuba recruited 32 post-menopausal women and assigned them to one of three groups: The first group acted as the controls, the second group underwent an aerobic exercise training regime, and the third group received curcumin supplements (Theracurmin from Theravalues Corporation, Tokyo).

The curcumin used in the study was described as a “highly absorptive curcumin dispersed with colloidal nanoparticles”. A daily dose of 25 milligrams was provided.

The study lasted for eight weeks, after which the results showed that FMD increased significantly and equally by about 1.5% in both the exercise and curcumin groups, compared with no changes in the control group.

“The mechanism responsible for the curcumin ingestion induced improvement in endothelial function is unclear,” said the researchers.

“Curcumin exerts anti-inflammatory and anti-oxidative effects by inhibiting tumor necrosis factor-alpha (TNF-alpha), suggesting that its effect on endothelial function may be mediated by the suppression of inflammation and/or oxidative stress via down-regulation of TNF-alpha. However, TNF-alpha levels were mot assessed in this study.

“Further studies are warranted to clarify the mechanism underlying the effect of curcumin on endothelial function.”

The study was funded by the Japan Society for the Promotion of Science.

Source: Nutrition Research
Published online ahead of print, doi: 10.1016/j.nutres.2012.09.002
“Curcumin ingestion and exercise training improve vascular endothelial function in postmenopausal women”
Authors: N. Akazawa, Y. Choi, A. Miyaki, Y. Tanabe, J. Sugawara, R. Ajisaka, S. Maeda

Related products

Live Supplier Webinars

Polyphenols tipped to become the way to innovate in Sports Nutrition
Fytexia
Alpha & Omega in Sports Nutrition – Using Omega 3’s and A-GPC to improve performance and recovery.
KD Pharma
Orally bioavailable standardized botanical derivatives in sport nutrition: special focus on recovery in post-intense physical activities
Indena
Collagen in motion: move freely and keep your injuries in check
Leading manufacturer of gelatine and collagen peptides
Life’s too short for slow proteins. Whey proteins hydrolysates: Fast delivery for enhanced performance
Arla Foods Ingredients
What it Takes to Compete and Win in Today’s Sports Nutrition Market
Capsugel
Sports Nutrition Snapshot: Key regional drivers and delivery format innovations
William Reed Business Media
Gutsy performance: How can microbiome modulation help athletes and weekend warriors
William Reed Business Media
Pushing the boundaries: Where’s the line between ‘cutting edge nutrition’ and doping
William Reed Business Media

On demand Supplier Webinars

High-amylose maize starch may reduce the risk of type 2 diabetes: what does this qualified health claim mean?
Ingredion
Balancing Innovation and Risk in Sports Nutrition Ingredients
NSF-International
Explaining bio-hacking: is there a marketing opportunity for food companies?
William Reed Business Media
Personalized Nutrition – how an industry can take part in shaping the future of Nutrition
BASF Nutrition & Health
Find out Nutritional and ingredient lifecycle solutions and strategies!
Roquette
Is the time rIpe for I-nutrition?
William Reed Business Media
The Advantage of Outsourcing Fermentation-based Manufacturing Processes
Evonik Health Care
All supplier webinars