SUBSCRIBE

Breaking News on Supplements, Health & Nutrition - Europe US edition | APAC edition

Read more breaking news

 

 

Citicoline wins EU novel foods approval - in medical foods and food supplements

By Shane Starling+

18-Jul-2014
Last updated on 08-Aug-2014 at 12:39 GMT2014-08-08T12:39:17Z

Citicoline wins EU novel foods approval - in medical foods and food supplements

Citicoline has won EU novel foods approval for use in food supplements and medical foods after appeasing member state concerns about the phospholipid precursor being a medicine.

Applicant Kyowa Hakko Europe welcomed the July 1 affirmation in EU law books that permits its use in food supplements at 500 mg/day and in medical foods at 250 mg/day with a maximum recommended daily intake of 1000 mg/day across the European Union’s 28 member states.

Kyowa Hakko has been able to market the ingredient on its cognitive benefits although the European Food Safety Authority (EFSA) did not back such benefits when it looked at the available science a few years ago.

EFSA’s Panel on Dietetic Products, Nutrition and Allergies (NDA) backed citicoline for lipid and homocysteine metabolism and liver function but not brain function.

Path to shelf

The novel foods application stalled after the Irish food agency gave approval in 2012 when member states raised the medicines question.

The European Commission passed the matter to EFSA which issued a positive safety opinion late last year, making special mention that citicoline should not be consumed with certain medicines and never by children.

It also acknowledged that in some cases citicoline could be classified as both a medicine and a food.

Citicoline is the generic name for CDP-choline (choline cytidine 5’-pyrophosphate), a precursor to the likes of phosphatidylcholine, phosphatidylserine and phosphatidyl-ethanolamine which all have been linked to brain health.

Citicoline has been used by the Kyowa Hakko and others in the US since the 1980s and the nutrient also won Generally Recognized As Safe (GRAS) status in 2009 from the US Food and Drug Administration (FDA).

That approval was for levels of 250 mg per serving in categories including beverages, breakfast cereals, chewing gum, pastas, hard candies, milk products, fruit juices and soft candy.

Related products

Live Supplier Webinars

Polyphenols tipped to become the way to innovate in Sports Nutrition
Fytexia
Orally bioavailable standardized botanical derivatives in sport nutrition: special focus on recovery in post-intense physical activities
Indena
Collagen in motion: move freely and keep your injuries in check
Leading manufacturer of gelatine and collagen peptides
Life’s too short for slow proteins. Whey proteins hydrolysates: Fast delivery for enhanced performance
Arla Foods Ingredients
What it Takes to Compete and Win in Today’s Sports Nutrition Market
Capsugel
Sports Nutrition Snapshot: Key regional drivers and delivery format innovations
William Reed Business Media
Gutsy performance: How can microbiome modulation help athletes and weekend warriors
William Reed Business Media
Pushing the boundaries: Where’s the line between ‘cutting edge nutrition’ and doping
William Reed Business Media
Alpha & Omega in Sports Nutrition – Using Omega 3’s and A-GPC to improve performance and recovery.
KD Pharma

On demand Supplier Webinars

High-amylose maize starch may reduce the risk of type 2 diabetes: what does this qualified health claim mean?
Ingredion
Balancing Innovation and Risk in Sports Nutrition Ingredients
NSF-International
Explaining bio-hacking: is there a marketing opportunity for food companies?
William Reed Business Media
Personalized Nutrition – how an industry can take part in shaping the future of Nutrition
BASF Nutrition & Health
Find out Nutritional and ingredient lifecycle solutions and strategies!
Roquette
Is the time rIpe for I-nutrition?
William Reed Business Media
The Advantage of Outsourcing Fermentation-based Manufacturing Processes
Evonik Health Care
All supplier webinars