Quercetin is a ubiquitous polyphenol in nature whose antiviral properties have been investigated in numerous studies. Unfortunately, the absorption of quercetin is very poor and makes it hardly effective. This problem has been overcome with the use of Quercetin Phytosome® which allows an absorption ten times higher than quercetin alone. The usefulness of this complex has also been validated by 2 controlled clinical studies, carried out on patients with COVID-19, in which the symptoms related to the infection were almost eliminated and the time to obtain the clearance of infection was halved.