Large zinc doses may raise prostate cancer risk

- Last updated on GMT

Related tags: Prostate cancer, Cancer, Zinc deficiency

Men who take large doses of zinc in supplements could be at
increased risk of prostate cancer, finds a study by researchers at
the US National Cancer Institute. The risk was only seen however at
levels far above those set by most national food agencies.

A high intake of zinc in supplements may raise the risk of prostate cancer, finds a recent study by a team at the US National Cancer Institute.

The researchers found that men taking more than 100mg of supplemental zinc daily were more than twice as likely to develop prostate cancer as men consuming less than this amount.

"Although we cannot rule out residual confounding by supplemental calcium intake or some unmeasured correlate of zinc supplement use, our findings, that chronic zinc oversupply may play a role in prostate carcinogenesis, warrant further investigation,"​ wrote the authors in this month's issue of the Journal of the National Cancer Institute​ .

Zinc deficiency, associated with many diseases, including chronic liver disease, sickle cell disease and diabetes, is thought to affect around 2 billion people in the developing world, however in the US and Europe some people could be consuming too much of the nutrient in supplements. Nevertheless, the Health Food Manufacturers' Association in the UK recommends an upper safety level of 15mg zinc for daily self-supplementation while the EU Scientific Committee on Food suggests total daily intake should not exceed 25mg. Both of these are far from the 100mg levels tested by the researchers.

Using a 14-year follow-up trial, the Health Professionals Follow-Up Study, the researchers identified 434 cases of advanced cancer. Supplemental zinc, often taken to prevent or treat colds, at doses of up to 100 mg per day was not associated with prostate cancer risk but compared with nonusers, men who consumed more than 100 mg of supplemental zinc daily had a relative risk of advanced prostate cancer of 2.29. This increased to 2.37 for men adding zinc to their diet for 10 years or more.

Related topics: Research, Suppliers, Men's Health

Related news

Show more

Related products

show more

A Promising Product for Comprehensive Men's Health

A Promising Product for Comprehensive Men's Health

Chemical Resources (CHERESO) | 17-Jun-2019 | Clinical Study

Testosterone deficiency is increasingly recognized as a significant health problem in men. Testosterone deficiency can adversely affect sexual function,...

Protecting Protein, Protecting the Industry

Protecting Protein, Protecting the Industry

European Specialist Sports Nutrition Alliance | 17-Jul-2018 | Technical / White Paper

Protein spiking, or adulteration, is an emerging issue in Europe. ESSNA knows that as a result of some uncertainty around the regulatory definition of...

Related suppliers

Follow us

Featured Events

View more

Products

View more

Webinars