Study finds single dose of ATP ingredient boosts muscular power, endurance

By Hank Schultz

- Last updated on GMT

©Getty Images - Mel Curtis
©Getty Images - Mel Curtis

Related tags Sports nutrition products Sports nutrition sector Sports Nutrition Summit USA

A new study on PEAK ATP, a branded ingredient marketed by TSI Group, shows the molecule can have significant sports performance benefits with a single, acute dose.

The study, which was the work of authors based in the US and Brazil, was presented as a poster at a recent meeting of the International Society of Sports Nutrition.  The manuscript is under review for formal publication.

PEAK ATP has been researched for years in various settings.  According to Dr Ralf Jaeger, PhD, MBA, one of the study’s coauthors, this is the only the second study to validate the ingredient’s acute effects, which were significant.

Three arm study tests effective dose

The study was set up as a three arm, randomized, placebo-controlled trial designed to test 400 mg, 200 mg and 100 mg dosages of the ingredient.  The researchers recruited 20 active young men for the study, who lifted weights after each of the acute PEAK ATP administrations.  There was a one week washout period between arms.

The results found a significant effect of acute administration at the 400 mg dose.  Participants lifted about 13% more weight in the single repetitions meant to test peak power and completed about 7% more repetitions in the portion of the test designed to test the ingredient’s effects on muscular endurance.

Dr Jaeger said that while the 400 mg acute dose results are significant, the study also has implications for chronic use of the ingredient.  At the lower doses the subjects felt better during the peak strength and muscular endurance tests, which could translate into a long term benefit.

“When it comes to athletic performance, the acute dose needed is 400 mg. However, even as little as 100 mg showed an effect on how exerted athletes feel during workouts. This could translate into meaningful benefits on strength, power and muscle mass during a chronic training program, as it indicates that athletes can work out harder and more frequently, and consequently could see faster training adaptations,” ​Dr Jaeger told NutraIngredients-USA​.

Kolb: One time benefit significant for industry

TSI Group president Larry Kolb said PEAK ATP is a clinically validated and patented form of Adenosine 5’-Triphosphate (ATP) Disodium that is identical in structure to ATP produced and used by the human body. He said the new results could bolster the use of the ingredient across a range of applications.

“These results confirm the immediate benefits of PEAK ATP for athletes, weekend warriors and everyday exercisers. We feel that there is a huge advantage for consumers who are able to feel the performance benefit from the first use onward, instead of waiting for weeks for supplementation to take full effect. PEAK ATP helps exercisers to push harder during high-intensity and/or exhaustive exercise. And because PEAK ATP supports increased work volume, it can help anyone make the most of time spent exercising,” Kolb said.

Sports & Active Nutrition Summit 2022

Dr Jaeger will present results of his latest research into a pair of additional ingredients at NutraIngredients-USA’s Sports & Active Nutrition Summit​, which returns this year as an in-person event in San Diego, CA on Feb. 14-16.  For more info, see the event homepage​.

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