Omega-3 study doses were too low for heart protection, claims GOED

By Caroline Scott-Thomas

- Last updated on GMT

Related tags Omega-3 fatty acids Omega-3 fatty acid

The Global Organization for EPA and DHA Omega-3 (GOED) has said dosage levels were too low in a study suggesting EPA/DHA enriched spreads do not protect heart attack sufferers from further cardiac events.

The study, published in the New England Journal of Medicine​, aimed to examine how daily intake of margarine enriched with 400mg combined EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) affected elderly individuals who had suffered a heart attack more than four years previously. It found “no effect on the rate of major cardiovascular events”.

But GOED, an organization that represents about 85 omega-3 suppliers, has said this conclusion should not negate earlier findings of the fatty acids’ benefits at higher doses. It said there were several problems with the study, including a relatively low dosage of omega-3, and that all subjects were given blood pressure and cholesterol-lowering treatments during the study period.

Executive director of GOED Adam Ismail said: "While 400 mg of combined EPA/DHA provides a sufficient dose for most healthy individuals, previous clinical studies in individuals having suffered a heart attack suggest that 1,000 mg+ of EPA/DHA decreases the incidence of secondary cardiovascular events — more than twice the dose administered in the recently published study."

One such study, published in Clinical Nutrition ​earlier this year, examined the impact of three grams of omega-3 per day in a dairy drink, and found improvements in a range of cardiovascular risk factors, including cholesterol levels, triacylglyceride levels, and the ratio of AA (arachidonic) acid to EPA.

The European Food Safety Authority has issued an opinion on ALA (alpha-linolenic acid), saying it supports lowering of blood cholesterol, but EPA/DHA were not backed for the same effect in an opinion published in October last year.

Ismail added: "GOED supports research that examines all health effects of consuming EPA- and DHA-rich sources, as our members' focus is on educating consumers on the complexities of EPA/DHA consumption...GOED is hopeful that the study's results showing the positive effect of low-dose EPA/DHA on diabetic subjects will yield further examination."

Omega-3 fatty acids, most notably DHA and EPA, have been linked to a wide range of benefits beyond heart health, including reduced risk of certain cancers, healthy foetal development, joint health, and improved behaviour and mood.

Related news

Show more

Related products

show more

Harness the power of algae for omega-3 innovation

Harness the power of algae for omega-3 innovation

Content provided by dsm-firmenich | 08-May-2024 | Insight Guide

Algal-sourced omega-3s have limitless potential, able to scale to meet the needs of our planet’s population with twice the potency – naturally – and all...

Sweetening solution for active nutrition

Sweetening solution for active nutrition

Content provided by ADM | 19-Feb-2024 | Case Study

When you add GrainSweet® Liquid Maltodextrin to your active nutrition applications, you get the production efficiencies, clean labels, and clean tastes...

Nutritional Solutions for Women's Health

Nutritional Solutions for Women's Health

Content provided by INNOBIO Corporation Limited | 04-Oct-2023 | White Paper

INNOBIO provides innovative solutions for women to overcome a variety of health challenges throughout the life cycle, from emotional health, PMS management,...

Omega-3:Nutrition and Application Insight

Omega-3:Nutrition and Application Insight

Content provided by Cabio Biotech (Wuhan) Co., Ltd | 31-Jul-2023 | White Paper

Omega-3 long-chain polyunsaturated fatty acids (PUFAs) have numerous positive health benefits and are among the most extensively studied micronutrients....

Related suppliers

Follow us

Products

View more

Webinars