Ubiquinol supports mitochondrial function in women’s health

Ubiquinol is a key component of the mitochondrial electron transport chain in cells, where it facilitates adenosine triphosphate (ATP) production – the body’s primary energy currency.

Beyond energy generation, ubiquinol’s potent antioxidant properties help reduce oxidative stress that accelerates the decline of mitochondrial function. Clinical studies have shown that supplementation with ubiquinol supports overall healthy ageing and optimal wellbeing, cardiovascular health, exercise performance, cognitive function, menopause and reproductive health, while also helping to mitigate fatigue and muscle symptoms experienced by some individuals taking cholesterol-lowering medications.

With over 100 published studies and decades of performance data, ubiquinol is emerging as a scientifically-validated ally for maintaining cellular vitality and supporting health across all life stages.

Figure 1: Role of Ubiquinol in Oxidative Phosphorylation and Antioxidant Defence¹⁻² — Figure 1: Role of Ubiquinol in Oxidative Phosphorylation and Antioxidant Defence.¹⁻²

The mitochondria – ageing connection

Mitochondria generate over 90% of cellular energy through ATP production – a process critical for maintaining physiological function.³ However, mitochondrial efficiency declines with age due to cumulative oxidative damage, mitochondrial DNA mutations, inflammatory signalling and accelerated cell senescence.

Ubiquinol is integral to mitochondrial health and ATP/energy production. Present in each of the 1000-5000 mitochondria found in over 30-40 trillion cells throughout the body, ubiquinol also functions as a lipid-soluble antioxidant, counteracting oxidative stress and stabilising mitochondrial membranes.⁴

As endogenous levels of ubiquinol decline with age, mitochondrial function becomes further impaired – contributing to biological ageing, fatigue, cognitive decline, reduced metabolic efficiency, and increased vulnerability in systems dependent on its antioxidant and anti-inflammatory actions.

Science has shown that supplementation with ubiquinol may help preserve cellular energy production across all life stages, from pre-conception to healthy ageing, support physical endurance and promote overall health and vitality as the body ages.

Cardiovascular health: A lifelong priority

Cardiovascular disease remains a leading cause for health concern, globally, with risk increasing significantly with age due to factors such as vascular stiffness, oxidative stress and dyslipidaemia.⁵

Ubiquinol supports cardiovascular health by improving endothelial function, enhancing nitric oxide bioavailability and reducing LDL oxidation. It also helps maintain healthy cholesterol and blood lipid levels – factors essential to vascular resilience.⁶⁻¹⁰

This combined mitochondrial and vascular support is particularly relevant for older adults and for those taking cholesterol-lowering medications, which may deplete endogenous ubiquinol. Supplementation has been shown to support improved cardiovascular outcomes and help reduce associated symptoms such as fatigue and muscle weakness.¹¹⁻¹³

Musculoskeletal resilience and exercise recovery

Preserving musculoskeletal function is central to healthy ageing. Ubiquinol has been shown to support exercise endurance, reduce muscle damage and support post-workout recovery by combating oxidative stress and preserving mitochondrial integrity.¹⁴⁻¹⁷

Cognitive function and mental performance

Modern life places continual demands on cognitive clarity, sustained focus and psychological resilience whilst juggling multiple roles in life.

The brain is among the most metabolically active organs in the body, requiring a continuous supply of mitochondrial energy to support memory, attention and mental performance. Ubiquinol contributes to cognitive function by supporting mitochondrial efficiency and helping to protect against oxidative stress in neural tissues.

Clinical research has shown that 100 mg of ubiquinol daily for 34 weeks improved attentiveness, memory and executive function in adults, highlighting its potential to support cognitive function across the lifespan.¹⁸

Reproductive health and fertility in men and women

Today, fertility is often postponed until later reproductive years – an age range associated with increased oxidative stress and reduced mitochondrial efficiency, both of which can compromise oocyte and sperm quality.

Ubiquinol supports male and female reproductive function by enhancing mitochondrial energy production and antioxidant protection in reproductive tissues.¹⁹⁻²⁰ Ubiquinol improves sperm motility, morphology, density and oxidative status, offering multiple benefits for fertility optimisation.¹⁹⁻²¹

Menopause: Energy, mood and quality of life

Amid the growing focus on healthy longevity, women navigate a complex interplay of hormonal, metabolic and physiological changes across their lifespan. From reproductive health and cognitive performance to cardiovascular resilience and the menopausal transition, each stage demands sustained cellular energy and mitochondrial support.

The transition through perimenopause and menopause is often accompanied by a cascade of symptoms including fatigue, brain fog, sleep disturbances and mood fluctuations, driven in part by a decline in oestrogen, which further exacerbates mitochondrial dysfunction.

In a survey of 200 women, ubiquinol’s role in energy production and oxidative defence has been shown to improve sleep quality, symptoms of stress, enhance mood and support quality of life (QoL) in menopausal women.²² Clinical research demonstrates that 100 mg a day of ubiquinol over 12 weeks can significantly improve menopausal symptoms and QoL scores.²³

Figure 2: Ubiquinol Supports Healthy Ageing and Women’s Health²²⁻²³ — Figure 2: Ubiquinol Supports Healthy Ageing and Women’s Health.²²⁻²³

Energy, vitality and metabolic balance for women

Across menstruation, motherhood and menopause, mitochondrial output is intimately linked to women’s energy, metabolic regulation and stress resilience. Ubiquinol supports these processes by enhancing cellular energy and reducing systemic oxidative burden, contributing to improved metabolic adaptability.²⁴⁻²⁷

Science-backed and clinically trusted

Kaneka Ubiquinol™ is the multi award-winning sole global supplier of ubiquinol, bioidentical to that found naturally in the body. Manufactured via a patented Japanese precision yeast fermentation process and backed by over 100 studies and 80 patents, it sets the global benchmark for R&D, manufacturing, mitochondrial support, stability and bioavailability.

Championing healthy ageing and women’s health

Building on the growing body of science linking mitochondrial health with energy, healthy ageing and women’s wellbeing, Kaneka Ubiquinol™ is bringing these insights directly to delegates at Vitafoods Asia 2025.

As the category sponsor for Healthy Ageing & Longevity and a finalist in the Nutraingredients Awards – Innovation in Women’s Health, Kaneka Ubiquinol is proud to lead the global conversation on mitochondrial health, scientific innovation, and women’s health.

At the heart of this commitment is the Kaneka Genki Power Forum at Stand C17 - an immersive education program running across all three days of the conference. Award-winning pharmacist Bobby Mehta, alongside practitioner-educators Monitar Tan and Jeannie Kwa, will deliver expert sessions exploring the science of mitochondrial health and its impact on energy, cardiovascular support, cognition, women’s health and healthy ageing.

Delegates can also hear Mr Mehta present his keynote, ‘Mitochondrial Health & Ubiquinol: The New Frontier in Optimal Wellbeing’ on the Vitafoods Mainstage (17 September, 2:30pm) and speak on mitochondrial health and healthy ageing at the Vitafoods Asia Healthy Ageing Summit (18 September, 10:10am).

Join Kaneka Ubiquinol Pavilion (Stand C17) to experience the Genki Power Forum, connect with the experts, and learn how clinically validated, precision-fermented Ubiquinol can elevate nutraceutical formulations and support evidence-based healthcare.

Find out more information about the science of ubiquinol in mitochondrial health and function.

*Always read the label and follow the directions for use. Consult your healthcare professional to establish if ubiquinol is suitable for your needs.

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