Synbiotics may target new areas, animal study

Related tags High fat diet Probiotic

Combining prebiotic and probiotic ingredients, commonly known as a
synbiotic, has different effects from those of the individual
supplements and does not simply result in additive or synergistic
effects, report German researchers studying the effects on rats.

Probiotics have been shown to improve immunity in animals and humans but the team from Germany's Federal Research Centre for Nutrition notes that the effects of prebiotics on systemic and intestinal immunity have not been investigated.

There is even less reasearch on synbiotic ingredients but their findings show that combining prebiotics and probiotics could open up new areas of health benefit.

The researchers tested the effects of three different supplements - probiotic bacteria Lactobacillus rhamnosus GG​ and Bifidobacterium lactis Bb12​, a prebiotic supplement of inulin enriched with oligofructose and a combination of both of these - added to a high fat diet fed to rats.

Writing in this month's Journal of Nutrition​ (134:153-156), they report that the synbiotic supplement increased secretory immunoglobulin A (sIgA) production in the ileum compared the with control high fat diet alone. It also decreased the oxidative burst activity of blood neutrophils compared with rats fed probiotics only.

The prebiotic supplement enhanced the production of interleukin-10 in PP as well as the production of sIgA in the cecum compared with controls. The probiotic supplement modestly affected immune functions, whereas systemic immunomodulatory effects were observed in rats fed synbiotics.

Many market analysts have forecast increasing sales of synbiotic products but further research will be needed before consumer awareness can be tapped. Further marketing is still needed before probiotic sales reach their potential, according to a recent Frost & Sullivan report.

Related news

Related products

show more

Organic S. boulardii: A Probiotic Breakthrough by Lallemand

Organic S. boulardii: A Probiotic Breakthrough by Lallemand

Lallemand Health Solutions. Quality Probiotics. Complete Solutions. | 26-Jan-2023 | Infographic

Lallemand Health Solutions is launching the first and unique organic version of probiotic yeast Saccharomyces boulardii to mark the hundredth anniversary...

Adopting B. longum BB536 in infant formula

Adopting B. longum BB536 in infant formula

Morinaga Milk Industry Co., Ltd. | 10-Jan-2023 | Technical / White Paper

Infant milk formula is one of the fastest-growing product categories in the baby food market, with China accounting for almost half of the global market...

Follow us


View more