Acetyl-L-carnitine may ease pain from diabetes condition

- Last updated on GMT

Related tags: Pain, Diabetes

The vitamin-like substance acetyl-L-carnitine appears to help ease
the pain caused by diabetic neuropathy, a common complication of
diabetes that results in painful damage to nerves.

Researchers from Italian L-carnitine manufacturer Sigma-Tau and Wayne State University in Detroit evaluated data from two randomized placebo-controlled trials carried out over a year on more than 1,200 diabetic patients in the US, Canada, and Europe.

The studies included tests on both 500mg and 1,000 mg doses of acetyl-L-carnitine daily.

Writing in the January issue of Diabetes Care​ (28:89-94), the researchers report that pain, 'the most bothersome symptom' of the condition, was significantly improved in one study and in the combined cohort taking the 1,000 mg dose.

Pain relief was greatest among those who had diabetes for the shortest time period, they noted, and these patients also showed improvements in nerve structure and perception of vibration.

Diabetes, and particularly type 2 diabetes, is rising fast around the world as a result of the increasing tendency towards overweight. The number of people in the UK with diabetes has surged to 1.8 million from 400,000 in just eight years, according to recent figures, with most of these -1.5 million - suffering from type 2 diabetes.

While longer studies are needed to examine the full effect of acetyl-L-carnitine on neuropathic pain, researchers suggest that it could also help delay progression of the condition or reduce its severity.

Related news

Show more

Related products

show more

Phytosome: the biomimetic delivery system

Phytosome: the biomimetic delivery system

Indena: the botanical ingredient of Health Food industry | 07-Oct-2019 | Application Note

Bioavailability is widely recognized as a central issue in the nutraceutical field. With almost a century of history on scientific know-how on its site,...

20 Years Palm Tocotrienols Brain Health Research

20 Years Palm Tocotrienols Brain Health Research

ExcelVite Sdn. Bhd. | 25-Sep-2019 | Technical / White Paper

Research of Vitamin E tocotrienol in brain health and neuroprotection began twenty years ago.
Today, other health benefits have been discovered...

Related suppliers

Follow us

Featured Events

View more

Products

View more

Webinars