MSM provides pain relief for OA sufferers, says study

- Last updated on GMT

Related tags: Msm, Rheumatoid arthritis

Anti-inflammatory MSM (methylsulfonylmethane) has added to the
store of evidence pointing to its health benefits with a new study
suggesting that it significantly reduces pain endured by
osteoarthritis (OA) sufferers, reports Jess Halliday.

The randomized, double-blind, placebo-controlled clinical trial led by Linda Kim of the Southwest College of Naturopathic Medicine involved 50 male and female suffers of mild to moderate knee OA pain, aged 40 to 76 years.

Divided into two groups, the participants took either a twice-daily 3g oral dose of MSM or a placebo over a 12-week period.

The pain relief effects were assessed using Western Ontario and McMaster University Osteoarthritis Index visual analogue scale (WOMAC).

Compared to the placebo, MSM was seen to deliver a significant reduction in pain scores (P=0.019) and physical function impairment (p=0.044).

Participants taking the MSM were also seen to experience an improvement in their performance of the activities of daily living (P=0.021).

No adverse events, such as those commonly reported with NSAIDs and cyclooxygenase-2 inhibitors, were identified during the short-term intervention.

The results of the study were presented at Vitafoods earlier this month by Jeremy Appleton, director of scientific affairs and R&D at Cardinal Nutrition​, which supplied MSM for the trial in the form of its OptiMSM product.

MSM occurs naturally, but in quantities too small for extraction. According to Appleton, this means that all commercial quantities must be synthesized.

When manufactured correctly, commercial MSM is chemically identical to that found in nature, he said. As well as its use as an anti-inflammatory, previous studies have suggested applications for rheumatoid arthritis, cancer prevention, lupus, hayfever and snoring.

"We do expect this study to open up new markets for OptiMSM, as certain brands are only interested in ingredients that have peer-reviewed, published research,"​ Appleton told

The study has not yet been accepted for publication in a journal, but it is hoped that it will be in the near future.

Related topics: Minerals, Bone & joint health

Related news

Show more

Related products

show more

Children’s Bones Need Vitamins K2 & D3

Children’s Bones Need Vitamins K2 & D3

NattoPharma – Gnosis by Lesaffre | 27-Sep-2021 | Data Sheet

Childhood is a crucial period for developing healthy bone mass. However, research shows children have 8-10x higher levels of inactive osteocalcin, which...

Turmacin®: Clean Label & Clinically Tested Turmeric

Turmacin®: Clean Label & Clinically Tested Turmeric

Natural Remedies Private Limited | 01-Sep-2021 | Product Presentation

Turmacin® is a clean label project-certified, clinically tested, and clinically safe turmeric extract. Turmacin® is rich in Turmerosaccharides® and doesn't...

Business case: private label iron supplements

Business case: private label iron supplements

PharmaLinea Ltd. | 18-May-2021 | Case Study

A line of clinically supported private label iron supplements by PharmaLinea is selling nearly 500.000 units/year in a market of under 20 million people.

Related suppliers

Follow us


View more