Resveratrol could prevent 'flu epidemics

- Last updated on GMT

Related tags: Resveratrol, Influenza

Resveratrol, a plant polyphenol found in red grapes, could be a
useful tool to combat the spread of 'flu, say Italian researchers.

Dr Anna Palamara of the Institute of Microbiology in Rome carried out in vitro​ and in vivo​ studies to investigate the chemical's effects on the replication of the influenza virus.

Palamara's hypothesis was based on earlier observations that the lifecycles of several viruses is influenced by the redox states of host cells, which play an important part in the replication of viruses.

In the in vitro​ study, she found that resveratrol "strongly inhibited"​ the replication of the influenza virus in cell cultures. The optimum effects were seen when resveratrol was administered three hours after the virus. Some small effect was seen when it was administered six hours after infection, but by nine hours it had no effect.

The researchers also determined that pre-treatment with resveratrol did not alter susceptibility to infection.

In the mouse model, rodents injected with resveratrol after inoculation with the influenza virus were seen to have 40 percent increased survival, compared with those that received a placebo.

Six days after infection, the resveratrol-treated mice had 98 percent lower pulmonary viral titers in their lung than the placebo mice.

Resveratrol's effects in this study are attributed to its antioxidant properties, and in particular the fact that it inhibits a cellular, rather than a viral function. Palamara said that further research into resveratrol's potential role in fighting 'flu epidemics is required, but that her study points to considerable potential.

Related topics: Respiratory health, Immune support

Related news

Related products

show more

Lonza Inc.

Lonza Inc.

Lonza - Capsugel | 02-Dec-2019 | Product Brochure

Making up 40% of the global population, Aspirationals are defined by their love to shop, desire to consume responsibly and belief that brands should have...

Robuvit® Shown to Improve Recovery from The Flu

Robuvit® Shown to Improve Recovery from The Flu

Horphag Research (USA) Inc. | 07-Nov-2019 | Research Study

Research shows Robuvit® French oak extract can help support recovery from influenza and boost the body’s defenses after the immune system is weakened from...

Related suppliers

Follow us

Featured Events

View more

Products

View more

Webinars