Science in brief

Folic acid supplements fail to boost mood in young people

- Last updated on GMT

Folic acid supplements fail to boost mood in young people

Related tags: Folic acid

Dietary supplements containing folic acid did not improve influence the incidence of mood disorder in young people with an increased familial risk of the condition, says a new study.

Data from epidemiological studies have suggested that low folate levels may increase the risk of depressive symptomatology in the general population leading to the hypothesis that folic acid supplements may influence mood.

However, in a randomized, double blind, parallel group, placebo-controlled trial with 112 young people with an increased familial risk of mood disorder, folic acid supplements at a dose of 2.5 milligrams per day did not significantly affect the incidence of mood disorder.

Data published in the Journal of Affective Disorders​indicated that, “there was post-hoc evidence that folic acid delayed the time to onset of mood disorder in those participants who became unwell.

“In addition, the mood disorders in the folate treated participants, when they occurred, tended to be clinically milder.”

Scientists from Oxford University in England noted that their study was limited by not recruiting the targeted number of subjects, and because the rate of onset of mood disorders was lower than they expected.

“Thus we cannot exclude that a larger participant sample or different experimental design would have shown a significant beneficial effect of folate prophylaxis.”

Source: Journal of Affective Disorders
Volume 167, Pages 306-11, doi: 10.1016/j.jad.2014.06.011
“Folic acid supplementation for prevention of mood disorders in young people at familial risk: A randomised, double blind, placebo controlled trial”
Authors: Sharpley AL, Hockney R, McPeake L, Geddes JR, Cowen PJ.

Related topics: Vitamins & premixes, Cognitive function

Related news

Show more

Related products

show more

20 Years Palm Tocotrienols Brain Health Research

20 Years Palm Tocotrienols Brain Health Research

ExcelVite Sdn. Bhd. | 25-Sep-2019 | Technical / White Paper

Research of Vitamin E tocotrienol in brain health and neuroprotection began twenty years ago.
Today, other health benefits have been discovered...

MenaQ7® Partners Benefit From K2 Outreach

MenaQ7® Partners Benefit From K2 Outreach

NattoPharma USA, Inc. | 22-Apr-2019 | Case Study

MenaQ7® K2 as MK-7 provides health benefits for all ages. That is a fact clinically proven by NattoPharma and communicated to practitioners and consumers...

Breakthrough in Women's Health

Breakthrough in Women's Health

Biosearch Life | 08-Apr-2019 | Clinical Study

A new study performed on women with polycystic ovary syndrome (PCOS) and fertility problems has been published in Gynecological Endocrinology. Results...

Outsmart brain-ageing in healthy older adults

Outsmart brain-ageing in healthy older adults

DIANA, FOOD DIVISION | 02-Apr-2019 | Technical / White Paper

What happens when you combine the brain health benefits of blueberries with those of grapes?
Both Canadian wild blueberries and French grapes are...

Related suppliers

Follow us

Featured Events

View more

Products

View more

Webinars