Bioiberica collagen reduces osteoarthritis symptoms in five days, study shows

By Kavitha Sivasubramaniam contact

- Last updated on GMT

© Bioiberica
© Bioiberica

Related tags: Bioiberica, Collagen, Joint health

Bioiberica’s type II collagen, Collavant n2, can reduce symptoms of osteoarthritis in just five days when combined with the herbal extract Boswellia serrata, new research suggests.

The clinical study, published in the International Journal of Research in Orthopaedics​, discovered the solution could ease joint discomfort. It was carried out to assess the efficacy and safety of a proprietary formulation of the two ingredients for people with knee osteoarthritis.

According to the global life science company, the positive findings “open up new opportunities for nutraceutical manufacturers seeking to bring science-backed, holistic solutions that combine on-trend ingredients to the growing mobility market​”.

A clinical trial

A total of 40 patients were recruited for the multicentric clinical trial, who took the 40mg Collavant n2 and 100mg Boswellia serrata​ solution once a day for a period of three months.

From the fifth day of the study a significant reduction in visual analogue scale (VAS) was noted, suggesting the combination was quickly and effectively relieving knee osteoarthritis-related plan.

Pain scores carried on declining over time, as observed in assessments after day 15, followed by days 30, 60 and 90. In comparison to the baseline, participants also felt less stiffness and improved physical function. They reported no significant side effects.

The results appeared to confirm the sustained impact of Collavant n2 in aiding joint health, as well as the safety of the solution.

Daniel Martínez Puig, Head of R&D Human Health at Bioiberica, says: “Boswellia serratais considered a potent anti-inflammatory and anti-arthritic herbal extract that may help to improve pain and physical function in patients with osteoarthritis. Likewise, Collavant n2 has demonstrated benefits in joint health at only 40mg per day. This makes both ingredients attractive options for innovation in the mobility space.”

Significant findings

Extracted from chicken sternum and produced through a strictly controlled process, Collavant n2 is a safe, naturally-sourced next generation collagen for innovation in the mobility space, according to Bioiberica. It claims a low dose of only 40mg per day can help people maintain healthy joints.

According to Martinez Puig, the number of product launches featuring collagen and herbal combinations has grown at a CAGR of 25% since 2017, and those containing native type II collagen and Boswellia serrata specifically have risen at a CAGR of 71% since 2018.

He adds: “Usually, when used alone, the benefits of Collavant n2 are experienced within one to two months, so we were very interested when our strategic partner in India shared the results of this study with us, showing that when used in combination with this herbal extract, the benefits were felt in just five days.

“This signifies that specific ingredients can bring unique and important advantages, like enhanced efficacy, when brought together in one solution. These findings therefore present an exciting opportunity for formulators looking to explore new combinations with trending ingredients, like native type II collagen and herbal extracts, and show the potential to unlock solutions that deliver novel benefits.”

Source: International Journal of Research in Orthopaedics

Published online: http://dx.doi.org/10.18203/issn.2455-4510.IntJResOrthop20205570

'AflaB2® and osteoarthritis: a multicentric, observational, post-marketing surveillance study in Indian patients suffering from knee osteoarthritis'

Authors: Atul V. Jain, Karun A. Jain, N. Vijayaraghavan

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