“With the surge in GLP-1 medication use for weight loss, we recognized a critical gap in the market for tailored nutritional support,” said Muriel Gonzalez, president of The Vitamin Shoppe. “GLP-1 medications can significantly impact appetite, digestion and nutrient absorption, making supplementation essential.”
The launch builds on the company’s Whole Health Rx telehealth platform which provides clinician-guided prescription access to GLP-1 and testosterone replacement therapy (TRT) medications.
‘Lose weight, not nutrients’
The new line is accompanied by a message notifying consumers that they are to “lose weight, not nutrients.” While GLP-1 drugs are recognized as an effective and rapid slim-down strategy, questions remain around the ramifications and sustainability of the injections for weight loss.
Concerns center around important nutrients that may be lost due to the appetite suppressing effects of GLP-1s, which work by delaying gastric emptying to make patients feel full longer. There are also the side effects like nausea, vomiting and constipation associated with the buildup of food and waste in the digestive tract.
“GLP-1 users face specific nutritional challenges and finding products tailored to these needs can be challenging,” said Tabitha Daley, a registered dietitian nutritionist with The Vitamin Shoppe who helped formulate the GLP-1 Support products.
“Our goal was to create an accessible, science-backed system that fills essential nutrient gaps, while also helping individuals feel their best throughout their weight-loss journey by addressing nutrition-related issues that are associated with GLP-1 drugs.”
The GLP-1 Support products
The new line—packaged as an easy-to-understand, one-stop-shop solution under the Whole Health Rx brand—offers protein, fiber, biotics, multivitamins and an all-in-one nutrient powder formulated with clinically studied, branded ingredients. It includes:
- GLP-1 Support Nutrient Powder: A meal replacement providing 25 g of protein, 24 essential vitamins and minerals, DigeZyme digestive enzymes (Sabinsa), fiber and a full serving of Truserv greens (FutureCeuticals) to help maintain lean muscle mass, support digestion and replenish key nutrients often depleted by reduced food intake.
- GLP-1 Support Protein: Formulated with 30 g of whey protein, 5 g of collagen for skin health and myHMB (TSI Group) and PeptiStrong (Nuritas) to help counteract muscle loss.
- GLP-1 Support Fiber: With 15 g of fiber per serving to support digestion, the blend includes antioxidant-rich Natureknit fruit and vegetable fiber (FutureCeuticals), Inavea acacia fiber (Nexira) and Fibersol-2 (ADM/Matsutani LLC), clinically shown to enhance GLP-1 activity.
- GLP-1 Support Synbiotic: The triple-action gut health solution combines PreForPro prebiotic (ADM/Deerland Probiotics & Enzymes), HOWARU Shape probiotic (DuPont Nutrition & Health) and ButyraGen postbiotic (NutriScience Innovations) to optimize digestion, immune health and Akkermansia production—a beneficial gut bacteria that has been linked to weight management and metabolic health.
- GLP-1 Support Multivitamins (Men’s & Women’s Formulas): Formulated with daily essential nutrients for energy, metabolism, brain, heart and immune health, as well as Suntheanine (Taiyo International) for stress support and ginger for occasional nausea.
The new line is available at The Vitamin Shoppe and Super Supplements stores and online at vitaminshoppe.com.


