One biohacker’s blueprint for healthspan optimization

Shawn Wells, RD, a biochemist and formulator with 25 years of industry experience, recently shared his daily healthspan optimization routine at the Nutra Healthspan Summit in London.

The biohacker told NutraIngredients that he prioritizes sleep by going to bed promptly by 8:30 every night and tracking key metrics using an Oura Ring and continuous glucose monitor. Wells also emphasized that frequent five-minute “exercise snacks” throughout the day are more beneficial for longevity than single workout sessions.

“Even if you were to work out one hour a day every day, [research has] shown that if you’re sedentary the other 23, it’s not going to undo that enough and doing these ‘exercise snacks’ every hour you’re awake for five minutes has a more potent effect on longevity than even working out for one hour,” he said.

In addition to lifestyle hacks, Wells, who has patented over 40 ingredients, recommended three key supplements for healthspan support: ergothioneine for mitochondrial health and cognition, dileucine for muscle protein synthesis and strength, and dihydroberberine for glucose control and muscle development.

“Berberine, you’ve probably heard, is ‘nature’s Ozempic,’ right? Dihydroberberine is 5 to 20 times more bioavailable, and also it lasts about twice as long in the plasma without the GI distress associated with berberine,” Wells said. “So it’s really like berberine 2.0 and has been pretty exciting, increasing AMP kinase, which is an anti-aging pathway that’s pretty key, as well as GLP-1 boosting about 86%.”

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During his fireplace chat with Stephen Daniells, PhD, editor-in-chief at NutraIngredients, Wells expressed excitement about emerging wearable technologies, noting that we are in the midst of a massive evolution of wearables that enable personalized health monitoring and optimization.

“There’s a lot that’s about to happen,” he said, pointing to recent developments like eye contacts that measure blood glucose and rings that can track key metrics like heart rate and other markers of stress. “It’s pretty exciting right now.”