Science shorts: Vitamin D, postbiotics, HMB protein, NMN in the spotlight

Science shorts NutraIngredients_Asia
Find out new research findings related to nutraceuticals in this news round-up. (Getty Images/Connect Images)

This round-up highlights the latest health and nutrition research, including new findings on vitamin D, postbiotics, HMB protein, NMN and more.

Daily vitamin D chocolate wafer achieves sufficiency in three months, study suggests

Doses of 600-800IU vitamin D were consistently associated with attaining sufficiency
Doses of 600-800IU vitamin D were consistently associated with attaining sufficiency (jarun011/Getty Images)

Daily supplementation of vitamin D3 at doses of 400–800 IU consumed as a chocolate wafer for 12 weeks significantly improved serum 25(OH)D concentrations in vitamin D-deficient young Indian women, according to a new study.

Researchers in India and Qatar observed that while a 400IU daily dosage was effective at eliminating deficiency, higher doses of 600-800IU were more consistently associated with attaining sufficiency, with 65.4% of participants receiving 800 IU/day normalizing their levels by week 12.

Explore related questions

Beta

“In this context, serum 25(OH)D serves as a robust biochemical marker of vitamin D status, reflecting the cumulative effects of dietary intake and endogenous synthesis,” they wrote in Nutrients.

Postbiotics use reduces gingival inflammation - Japan study

Gingivitis is the inflammation of the gums and occurs when microbial plaque  accumulates on the tooth surface due to ineffective tooth brushing.
Gingivitis is the inflammation of the gums and occurs when microbial plaque accumulates on the tooth surface due to ineffective tooth brushing. (Daria Kulkova/Getty Images)

The supplementation of heat-inactivated Lactiplantibacillus pentosus ONRICb0240 has been shown to benefit certain aspects of oral health, specifically gingival inflammation, in a six-week study that took place in Japan.

This is seen from the significant improvements to bleeding on probing percentage (BOP) - a criterion widely used to diagnose gingival inflammation - researchers wrote in the Journal of Periodontology.

There were also significant improvements to the Gingival Index (GI) - a scale that quantifies the degree of gingival inflammation, based on visual assessment of redness and swelling etc.

Beta-glucan oligosaccharides could lower cholesterol levels - Thai study

A new study from China reported that supplementation of B. breve BBr60 probiotics could lower cholesterol levels.
A new study from China reported that supplementation of B. breve BBr60 probiotics could lower cholesterol levels. (AlexeyBlogoodf/Getty Images)

A 12-week study in Thailand found that daily supplementation of beta-glucans, either β-1,3/1,6-glucan oligosaccharides or polysaccharides, could significantly reduce total cholesterol levels.

However, two weeks post-supplementation, cholesterol levels remained significantly lower than baseline only in the oligosaccharide group, suggesting a more sustained effect, researchers wrote in Food Science and Nutrition.

Similarly, low-density lipoprotein (LDL) levels were significantly reduced in the oligosaccharide group after 12 weeks, with the effect persisting for two weeks post-intervention. This effect was not seen in the polysaccharide group.

HMB protein aids functional outcomes in sarcopenic surgical patients - Abbott

HMB protein supplementation could improve functional outcomes such as walking distance and chair rises in sarcopenic surgical patients, despite no gains in muscle quality, says a new pilot study by Abbott Nutrition.
HMB protein supplementation could improve functional outcomes such as walking distance and chair rises in sarcopenic surgical patients, despite no gains in muscle quality, says a new pilot study by Abbott Nutrition. (manassanant pamai/Getty Images)

Taking a high-protein beta-hydroxy beta-methylbutyrate (HMB) supplement, together with physical exercise, was shown to improve functional outcomes in sarcopenic surgical patients in a six-month pilot study.

Writing in Nutrients, researchers pointed out that supplementation with high-protein HMB, alongside an exercise regimen, has significantly improved chair rise repetitions and the six-minute walk test at six months post-operation in sarcopenic patients who have undergone gastrointestinal surgery.

Anthropometric measurements such as mid-arm muscle circumference, mid-arm muscle area, weight and body mass index, also increased significantly at six months post-operation.

NMN shown to suppress post-exercise inflammation

Nicotinamide mononucleotide supplement, niacin, anti ageing vitamin. White pills forming shape to NMN letters on yellow background, copy space, top view.
NMN (beta-nicotinamide mononucleotide) is one of the forms of vitamin B3, or niacin (Mizina/Getty Images)

A new pilot study conducted in Taiwan showed that the supplementation of nicotinamide mononucleotide (NMN) could lower inflammation in young men who have undergone blood flow restriction-resistance exercise.

Specifically, NMN supplementation was reported to have lowered inflammatory cytokine mRNA expression, such as TNF-α, in skeletal muscle after blood flow restriction-resistance exercise.

Writing in the Journal of the International Society of Sports Nutrition, researchers said that this was the first human study to report the findings.